The Twins reassigned eight players to minor league camp on Sunday and optioned outfielder Max Kepler to Double-A.
Kepler was one-for-nine in four games this spring.
Jose Berrios and outfielder Byron Buxton were the top names on the list of players reassigned.
Berrios, a first-rounder in the 2012 draft, gave up one unearned run on seven hits in six innings this spring, striking out four.
Buxton, also a 2012 first-rounder, hit .125 in eight at bats.
The Twins also cut catchers Stuart Turner (2-for-4 in spring) and Mitch Garver (0-for-4), RHP Tyler Duffey (no appearances), LHPs Taylor Rogers (no appearances) and Ryan O'Rourke (9.00 ERA in one inning); and infielder Heiker Meneses (.125).