| RK | Overall | Player | TM | Age | POS | 2008 high | Destination |
| 1 | 3 | Madison Bumgarner | SF | 19 | LHP | Low Class A | High Class A |
| Pitching this young is very difficult to project, but he won't be a teenager come Aug. 1; can he arrive then? |
| 2 | 5 | Cameron Maybin | FLA | 21 | OF | Majors | Majors |
| His steals will be what he should be drafted for this year, but he figures to be able do everything long term. |
| 3 | 8 | Thomas Hanson | ATL | 22 | RHP | Double-A | Triple-A |
| Arizona Fall League is a hitter's league and it couldn't touch him. What an amazing talent on the verge. |
| 4 | 9 | Jeff Samardzija | CHC | 24 | RHP | Majors | Majors |
| If he wins the No. 5 spot in the Cubs rotation in spring, he might prove the most valuable on this list. |
| 5 | 10 | Colby Rasmus | STL | 22 | OF | Triple-A | Triple-A |
| He had a poor season, but he is a five-tool talent with tremendous swagger. He could really rebound this season. |
| 6 | 12 | Pedro Alvarez | PIT | 22 | 3B | DNP, signed late | Double-A |
| No. 2 overall pick in last June's draft can really mash and should be able to move quickly with rebuilding Pirates. |
| 7 | 16 | Michael Stanton | FLA | 19 | OF | Low Class A | High Class A |
| The Florida State League will give us a much better sense of how much monster power this guy really has. |
| 8 | 17 | Timothy Alderson | SF | 20 | RHP | Low Class A | High Class A |
| Bumgarner has trumped him in the Giants' system, but Alderson can make his case as a future ace in his own right. |
| 9 | 18 | Jason Heyward | ATL | 19 | OF | Low Class A | High Class A |
| Some see him as a top-5 or top-10 prospect, but it is really too early to tell because some others have bigger numbers. |
| 10 | 20 | Jarrod Parker | ARI | 20 | RHP | Low Class A | High Class A |
| The D-Backs crown jewel must now help them forget they traded away the likes of the A's Anderson and others. |
| 11 | 24 | Mat Gamel | MIL | 23 | 3B | Majors | Triple-A |
| His D is bad and his numbers were a lot better when LaPorta was protecting him in Double-A. His bat will play, though. |
| 12 | 26 | Alcides Escobar | MIL | 22 | SS | Double-A | Double-A |
| His power should develop, but the Brewers have to be satisfied with J.J. Hardy at SS. Perhaps Escobar moves to 2B? |
| 13 | 27 | Andrew McCutchen | PIT | 22 | OF | Triple-A | Triple-A |
| Five-tool talent can make an immediate impact in all Rotisserie leagues once he arrives; watch closely this spring. |
| 14 | 29 | Logan Morrison | FLA | 21 | 1B | High Class A | Double-A |
| His power numbers weren't quite there, but the FSL does have a lot of big ballparks that suppress homer totals. |
| 15 | 30 | Buster Posey | SF | 22 | C | Low Class A | High Class A |
| Early '08 first-round pick doesn't have a whole lot of a track record as a pro, but he could be the next Matt Wieters. |
| 16 | 32 | Carlos Carrasco | PHI | 22 | RHP | Triple-A | Triple-A |
| The Phillies might bring their prized pitching prospect along slowly this spring, but look out once he arrives. |
| 17 | 33 | Fernando Martinez | NYM | 20 | OF | Double-A | Triple-A |
| He is extremely raw and somewhat injury prone, but his bat is quick and his power should develop like the Mets hope. |
| 18 | 40 | Kyle Blanks | SD | 22 | 1B | Double-A | Double-A |
| Monster slugger could be an impact call-up this season, but that only happens if the Padres move Adrian Gonzalez. |
| 19 | 41 | Yonder Alonso | CIN | 21 | 1B | High Class A | High Class A |
| Miami product's power is legit and Baseball America thinks he can move Joey Votto to LF by next season. |
| 20 | 43 | Josh Vitters | CHC | 19 | 3B | Low Class A | Low Class A |
| A little behind Moustakas now after being drafted on the same level, but he played catch up nicely last season. |
| 21 | 45 | Todd Frazier | CIN | 23 | SS | High Class A | Double-A |
| It should be a great rivalry in the Reds system between Frazier and the Reds SS prospect that follows him on this list. |
| 22 | 46 | Chris Valaika | CIN | 23 | SS | Double-A | Triple-A |
| A level ahead of Frazier now, but our guess is Frazier proves more powerful; the better one is the one that stays at SS. |
| 23 | 47 | Brett Wallace | STL | 22 | 3B | Double-A | Double-A |
| He likely won't be a candidate to start out of spring training this year, but next year he very well could be ready. |
| 24 | 49 | Dexter Fowler | COL | 22 | RHP | Double-A | Triple-A |
| The Matt Holliday trade opens up a chance for him, but the question is how much speed and power will he display? |
| 25 | 57 | Jordan Zimmermann | WAS | 22 | RHP | Double-A | Triple-A |
| Nationals top pitching prospect figures to get a chance before the year is out, but can he win with that supporting cast? |
| 26 | 58 | Jhoulys Chacin | COL | 21 | RHP | High Class A | Double-A |
| There's something about him that just reminds us of Ubaldo Jimenez; he very well could help Fantasy owners this year. |
| 27 | 60 | Angel Salome | MIL | 23 | C | Majors | Triple-A |
| We see him hitting his way into at-bats this season, especially if Jason Kendall breaks down or the Brewers go young. |
| 28 | 63 | Matt Antonelli | SD | 23 | 2B | Majors | Triple-A |
| He is still better than Chase Headley in our eyes and a potential starter at second base for the Padres. |
| 29 | 65 | James McDonald | LAD | 24 | RHP | Majors | Triple-A |
| He is a candidate for the No. 5 spot in the rotation this spring, but we're not sure he is an elite arm long term. |
| 30 | 66 | Gaby Sanchez | FLA | 25 | 1B | Majors | Majors |
| Sanchez will compete with Dallas McPherson and Jorge Cantu for a starting job this spring; pop gives him a chance to star. |
| 31 | 70 | Jonathon Niese | NYM | 22 | LHP | Majors | Triple-A |
| He is a candidate for the No. 5 spot in the rotation this spring, but he really could use some time back in Triple-A. |
| 32 | 72 | Jordan Schafer | ATL | 22 | OF | Double-A | Triple-A |
| Substance suspension taints his prospects at little, but he still stands to help the outfield-needy Braves this season. |
| 33 | 75 | Angel Villalona | SF | 18 | 1B | Low Class A | High Class A |
| His age-level ratio is outstanding as is his power potential, but we are really yet to be impressed by him for some reason. |
| 34 | 77 | Gerardo Parra | ARI | 21 | OF | Double-A | Double-A |
| Speed is ahead of his power, but a huge winter is helping him enter the conservation for an impact in 2009. |
| 35 | 80 | Matt Dominguez | FLA | 19 | 3B | Low Class A | High Class A |
| Not quite in the class of Moustakas and Vitters among California 3B prospects, but his power came around last year. |
| 36 | 81 | David Freese | STL | 25 | 3B | Triple-A | Majors |
| With Troy Glaus' shoulder surgery, his 26 Triple-A homers could make him a sleeper to start on opening day. |
| 37 | 83 | Neil Walker | PIT | 25 | 3B | Triple-A | Triple-A |
| He might need a new position now that Adam LaRoche is in Pittsburgh and Alvarez is pushing him from lower in the system. |
| 38 | 84 | Jesse Todd | STL | 22 | RHP | Triple-A | Triple-A |
| The Cardinals don't have a rotation that figures to hold him back much when he is deemed ready by midseason. |
| 39 | 86 | Jason Castro | HOU | 21 | C | Low Class A | Low Class A |
| Stanford prospect is just getting started as a pro, but his offensive potential at the position makes him a must-stash. |
| 40 | 88 | Dominic Brown | PHI | 21 | OF | Low Class A | High Class A |
| Baseball America draws some Darryl Strawberry comparisons here, but the power really isn't there yet. |
| 41 | 95 | Daniel McCutchen | PIT | 26 | RHP | Triple-A | Triple-A |
| A key piece in the Xavier Nady deal, McCutchen should push his way into the rotation this season, if not out of spring. |
| 42 | 97 | Jason Motte | STL | 26 | RHP | Majors | Majors |
| The Cardinals could give him a look as closer, but we see a setup man. If he closes, he will be top 10 here. |
| 43 | 98 | Kenshin Kawakami | ATL | 33 | RHP | Japan | Majors |
| Smallish right-handed import is old for a rookie, but he could have a Hiroki Kuroda -like impact. |