| Last updated: Sat, May 12, 2012, 02:06 EDT |
| Date | Player | Pos. | Transaction |
| 5/8 | Akwasi Owusu-Ansah | S | acquired from waivers |
| 5/8 | Jake Rogers | P | acquired from waivers |
| 5/8 | Troy Woolfolk | CB | cut |
| 5/7 | Brashton Satele | LB | cut |
| 4/30 | Charley Hughlett | C | signed |
| 4/30 | Troy Woolfolk | CB | signed |
| 4/30 | Eddie Whitley | S | signed |
| 4/30 | Aston Whiteside | LB | signed |
| 4/30 | Andrew Szczerba | TE | signed |
| 4/30 | Lionel Smith | CB | signed |
| 4/30 | Darrell Scott | RB | signed |
| 4/30 | Tyrone Novikoff | T | signed |
| 4/30 | Isaac Madison | CB | signed |
| 4/30 | Ronald Leary | G | signed |
| 4/30 | Jeff Adams | T | signed |
| 4/30 | Levy Adcock | T | signed |
| 4/30 | Cole Beasley | WR | signed |
| 4/30 | Tim Benford | WR | signed |
| 4/30 | George Bryan | TE | signed |
| 4/30 | Taylor Dever | T | signed |
| 4/30 | Lance Dunbar | RB | signed |
| 4/30 | Harland Gunn | G | signed |
| 4/30 | Saalim Hakim | WR | signed |
| 4/30 | Adrian Hamilton | LB | signed |
| 4/30 | Donavon Kemp | WR | signed |
| 4/26 | Jermey Parnell | T | re-signed, Three-year contract (through 2014) |
| 4/23 | Marc Colombo | T | retired |
| 4/23 | Anthony Spencer | LB | re-signed/franchise, One-year contract (through 2012) |
| 4/23 | Marc Colombo | T | signed/unrestricted free agent, One-day contract |
| 4/16 | Kai Forbath | K | cut |
| 4/5 | Rudy Carpenter | QB | acquired from waivers |
| 3/22 | Isaiah Greenhouse | LB | signed |
| 3/19 | Kyle Kosier | G | cut |
| 3/16 | Nate Livings | G | signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/16 | Kevin Ogletree | WR | re-signed/unrestricted free agent, One-year contract (through 2012) |
| 3/15 | Brodney Pool | S | signed/unrestricted free agent, One-year contract (through 2012) |
| 3/15 | Dan Connor | LB | signed/unrestricted free agent, Two-year contract (through 2013) |
| 3/14 | Kyle Orton | QB | signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/14 | Brandon Carr | CB | signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/14 | Mackenzy Bernadeau | G | signed/unrestricted free agent, Four-year contract (through 2015) |
| 3/14 | Lawrence Vickers | RB | signed/unrestricted free agent, Two-year contract (through 2013) |
| 3/13 | Derrick Dockery | G | declared free agent |
| 3/13 | Abram Elam | S | declared free agent |
| 3/13 | Keith Brooking | LB | declared free agent |
| 3/13 | Bradie James | LB | declared free agent |
| 3/13 | Montrae Holland | G | declared free agent |
| 3/13 | Martellus Bennett | TE | declared free agent |
| 3/13 | Alan Ball | CB | declared free agent |
| 3/13 | Terence Newman | CB | cut |
| 3/13 | David Buehler | K | cut |
| 3/13 | Jon Kitna | QB | declared free agent |
| 3/13 | Mat McBriar | P | declared free agent |
| 3/13 | Sammy Morris | RB | declared free agent |
| 3/13 | Laurent Robinson | WR | declared free agent |
| 3/13 | Frank Walker | CB | declared free agent |
| 3/13 | Tony Fiammetta | RB | declared free agent |
| 3/13 | Chris Greisen | QB | declared free agent |
| 3/13 | Chauncey Washington | RB | declared free agent |
| 3/13 | Jesse Holley | WR | declared free agent |
| 3/13 | Kevin Ogletree | WR | declared free agent |
| 3/5 | Anthony Spencer | LB | Designated franchise player |
| 1/12 | Jon Kitna | QB | Taken off IR, back |
| 1/12 | Justin Taplin-Ross | S | signed |
| 1/12 | Baraka Atkins | LB | signed |
| 1/12 | Jon Kitna | QB | retired |
| 1/12 | Brashton Satele | LB | signed |
| 1/4 | Mario Butler | CB | signed |
| 1/2 | Orie Lemon | LB | signed |
| 1/2 | C.J. Wilson | CB | signed |
| 1/2 | Teddy Williams | WR | signed |
| 1/2 | Rob Callaway | DT | signed |
| 12/31 | Daniel Loper | G | cut |
| 12/31 | Chris Greisen | QB | Activated from the Practice Squad |
| 12/31 | Chris Jones | P | Activated from the Practice Squad |
| 12/31 | Mat McBriar | P | Placed on IR, left foot |
| 12/27 | Brandon Carter | G | practice squad addition |
| 12/26 | Daniel Loper | G | signed |
| 12/26 | Montrae Holland | G | Placed on IR, strained bicep |
| 12/23 | Chauncey Washington | RB | Activated from the Practice Squad |
| 12/23 | Daniel Loper | G | cut |
| 12/14 | Dwayne Harris | WR | Activated from the Practice Squad |
| 12/14 | Chris Greisen | QB | practice squad addition |
| 12/14 | Jon Kitna | QB | Placed on IR, back |
| 12/13 | C.J. Wilson | CB | practice squad addition |
| 12/13 | Mana Silva | S | signed |
| 12/13 | Sammy Morris | RB | signed |
| 12/13 | DeMarco Murray | RB | Placed on IR, fractured right ankle |
| 12/13 | Barry Church | S | Placed on IR, shoulder |
| 12/9 | Gerald Sensabaugh | S | re-signed, Five-year extension |
| 12/9 | Andre Holmes | WR | Activated from the Practice Squad |
| 12/9 | Phillip Tanner | RB | Placed on IR, hamstring |
| 11/30 | Akwasi Owusu-Ansah | WR | cut |
| 11/30 | Shaun Chapas | RB | Activated from the Practice Squad |
| 11/30 | Chauncey Washington | RB | practice squad addition |
| 11/17 | Chris Jones | P | practice squad addition |
| 11/15 | Chris Jones | P | cut |
| 11/15 | Daniel Loper | G | signed |
| More Transactions |
