| Last updated: Sat, May 26, 2012, 02:03 EDT |
| Date | Player | Pos. | Transaction |
| 5/23 | Brandon Peguese | LB | cut |
| 5/23 | Jerry Brown | LB | signed |
| 5/23 | Cassius Vaughn | CB | traded, for FB Chris Gronkowski |
| 5/22 | Josh Chapman | NT | signed/draft choice, Four-year contract (through 2015) |
| 5/19 | Justin Anderson | T | signed/draft choice, Four-year contract (through 2015) |
| 5/18 | Matt Murphy | G | cut |
| 5/18 | Zane Taylor | C | acquired from waivers |
| 5/18 | Brody Eldridge | TE | cut |
| 5/17 | David Legree | QB | signed |
| 5/16 | Chandler Harnish | QB | signed/draft choice, Four-year contract (through 2015) |
| 5/16 | Vick Ballard | RB | signed/draft choice, Four-year contract (through 2015) |
| 5/16 | LaVon Brazill | WR | signed/draft choice, Four-year contract (through 2015) |
| 5/16 | Tim Fugger | LB | signed/draft choice, Four-year contract (through 2015) |
| 5/15 | Mike Holmes | CB | cut |
| 5/15 | Andre Smith | TE | acquired from waivers |
| 4/30 | Steven Baker | T | signed |
| 4/30 | Cameron Chism | CB | signed |
| 4/30 | Kevin Eagan | LB | signed |
| 4/30 | Antonio Fenelus | CB | signed |
| 4/30 | Jason Foster | T | signed |
| 4/30 | Chris Galippo | LB | signed |
| 4/30 | Jabin Sambrano | WR | signed |
| 4/30 | Buddy Jackson | CB | signed |
| 4/30 | James Aiono | DE | signed |
| 4/30 | Dominique Jones | TE | signed |
| 4/30 | Deji Karim | RB | acquired from waivers |
| 4/30 | Brian Stahovich | P | signed |
| 4/30 | Griff Whalen | WR | signed |
| 4/30 | Chigbo Anunoby | DT | signed |
| 4/30 | Micah Pellerin | S | signed |
| 4/30 | Matt Merletti | S | signed |
| 4/30 | Hayworth Hicks | G | signed |
| 4/13 | Blair White | WR | cut |
| 4/4 | Brandon McKinney | NT | signed/unrestricted free agent, Two-year contract (through 2013) |
| 4/3 | Kyle Miller | TE | signed |
| 4/2 | Matt Overton | DE | signed |
| 3/24 | Ryan Diem | G | retired |
| 3/23 | Donnie Avery | WR | signed/unrestricted free agent, One-year contract (through 2012) |
| 3/23 | Drew Stanton | QB | traded, with 7th round pick for 6th round pick |
| 3/21 | Samson Satele | C | signed/unrestricted free agent |
| 3/19 | Mike McGlynn | C | signed/unrestricted free agent |
| 3/17 | Tom Zbikowski | S | signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/14 | Cory Redding | DE | signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/14 | Winston Justice | T | traded, for 6th-round pick in 2012 |
| 3/13 | Jamaal Anderson | DE | declared free agent |
| 3/13 | Kevin Bentley | LB | declared free agent |
| 3/13 | Tyler Brayton | DE | declared free agent |
| 3/13 | Kerry Collins | QB | declared free agent |
| 3/13 | Ryan Diem | G | declared free agent |
| 3/13 | Jerome Felton | RB | declared free agent |
| 3/13 | Pierre Garcon | WR | declared free agent |
| 3/13 | Anthony Gonzalez | WR | declared free agent |
| 3/13 | Quinn Ojinnaka | T | declared free agent |
| 3/13 | Dan Orlovsky | QB | declared free agent |
| 3/13 | Mike Pollak | G | declared free agent |
| 3/13 | Jamey Richard | G | declared free agent |
| 3/13 | Jeff Saturday | C | declared free agent |
| 3/13 | Ernie Sims | LB | declared free agent |
| 3/13 | Jacob Tamme | TE | declared free agent |
| 3/13 | Reggie Wayne | WR | declared free agent |
| 3/13 | Philip Wheeler | LB | declared free agent |
| 3/13 | Stevie Brown | S | declared free agent |
| 3/13 | Anthony Hill | TE | declared free agent |
| 3/13 | Jacob Lacey | CB | declared free agent |
| 3/13 | Eric Foster | DT | declared free agent |
| 3/13 | Reggie Wayne | WR | re-signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/9 | Joseph Addai | RB | cut |
| 3/9 | Dallas Clark | TE | cut |
| 3/9 | Melvin Bullitt | S | cut |
| 3/9 | Gary Brackett | LB | cut |
| 3/9 | Curtis Painter | QB | cut |
| 3/8 | Jake Kirkpatrick | C | signed |
| 3/8 | Trevor Vittatoe | QB | signed |
| 3/7 | Peyton Manning | QB | cut |
| 3/5 | Robert Mathis | DE | re-signed, Four-year extension (through 2015) |
| 3/5 | Robert Mathis | DE | Designated franchise player |
| 1/28 | A.Q. Shipley | C | signed |
| 1/27 | Dominic Rhodes | RB | suspension lifted |
| 1/20 | Mario Harvey | LB | signed |
| 1/19 | Jerrell Freeman | LB | signed |
| 1/17 | Darren Evans | RB | signed |
| 1/7 | Jarred Fayson | WR | signed |
| 1/5 | Jeremy Ross | WR | signed |
| 1/4 | Matt Murphy | G | signed |
| 1/4 | Ollie Ogbu | DT | signed |
| 1/4 | Mike Tepper | T | signed |
| 12/28 | Philip Wheeler | LB | Placed on IR, foot |
| 12/28 | Quan Cosby | WR | acquired from waivers |
| 12/7 | Mike McNeill | TE | practice squad addition |
| 12/6 | Kevin Bentley | LB | acquired from waivers |
| 12/6 | Mike Holmes | CB | Activated from the Practice Squad |
| 12/6 | Brandon King | CB | signed |
| 12/6 | Mike Tepper | T | practice squad addition |
| 12/6 | Drake Nevis | DT | Placed on IR, back |
| 12/5 | Terrence Johnson | CB | Placed on IR, forearm |
| 12/5 | Zac Diles | LB | acquired from waivers |
| 12/5 | Mike McNeill | TE | cut |
| 12/5 | Jerraud Powers | CB | Placed on IR, dislocated elbow |
| 12/3 | Mike McNeill | TE | Activated from the Practice Squad |
| 12/3 | Mike Tepper | T | cut |
| 12/1 | Mike McNeill | TE | practice squad addition |
| 12/1 | Dedrick Epps | TE | practice squad deletion |
| 11/30 | Jermale Hines | S | signed |
| 11/29 | Jarrett Brown | QB | practice squad addition |
| 11/29 | Mike McNeill | TE | cut |
| 11/29 | Stevie Brown | S | Placed on IR, hamstring |
| 11/29 | Scott Lutrus | LB | signed |
| More Transactions |
