| Last updated: Sat, May 19, 2012, 21:42 EDT |
| Date | Player | Pos. | Transaction |
| 5/15 | DeOn'tae Pannell | G | signed |
| 5/15 | Josh Victorian | CB | cut |
| 5/15 | Nick Hixson | CB | signed |
| 5/15 | Phil Trautwein | T | cut |
| 5/15 | Lawrence Wilson | LB | signed |
| 5/15 | Stephen Johnson | LB | cut |
| 5/15 | Nick Howell | G | cut |
| 5/15 | Dan Hoch | T | cut |
| 5/14 | Hutch Eckerson | T | signed |
| 5/11 | Marquis Johnson | CB | signed |
| 5/7 | Remi Ayodele | DT | signed |
| 5/2 | Will Smith | DE | suspended, 4 games (conduct detrimental to NFL) |
| 5/2 | Jonathan Vilma | LB | suspended, for 2012 (conduct detrimental to NFL) |
| 4/30 | Aderious Simmons | T | signed |
| 4/30 | Aaron Tevis | LB | signed |
| 4/30 | Johnny Thomas | S | signed |
| 4/30 | Tyrunn Walker | DE | signed |
| 4/30 | Laron Scott | CB | signed |
| 4/30 | Jerico Nelson | S | signed |
| 4/30 | Stephen Johnson | LB | signed |
| 4/30 | Dan Hoch | T | signed |
| 4/30 | Kevin Hardy | WR | signed |
| 4/30 | Jose Gumbs | S | signed |
| 4/30 | Brian Folkerts | C | signed |
| 4/30 | Adrian Davis | CB | signed |
| 4/30 | Travaris Cadet | RB | signed |
| 4/30 | Jake Byrne | TE | signed |
| 4/30 | Braylon Broughton | DE | signed |
| 4/30 | Malcolm Beyah | WR | signed |
| 4/30 | Kadarron Anderson | LB | signed |
| 4/30 | Chris Givens | WR | signed |
| 4/26 | John Kasay | K | re-signed/unrestricted free agent, One-year contract (through 2012) |
| 4/24 | Jonathan Casillas | LB | re-signed/restricted free agent, One-year contract (through 2012) |
| 4/20 | Jabari Greer | CB | re-signed, Three-year extension (through 2015) |
| 4/16 | Courtney Roby | WR | re-signed/unrestricted free agent |
| 4/16 | Jeremiha Hunter | LB | cut |
| 4/3 | David Hawthorne | LB | signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/24 | Curtis Lofton | LB | signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/23 | Chris Chamberlain | LB | signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/21 | Brodrick Bunkley | DT | signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/15 | Ben Grubbs | G | signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/13 | Turk McBride | DE | declared free agent |
| 3/13 | John Kasay | K | declared free agent |
| 3/13 | Tory Humphrey | TE | declared free agent |
| 3/13 | John Gilmore | TE | declared free agent |
| 3/13 | Pat McQuistan | T | declared free agent |
| 3/13 | Robert Meachem | WR | declared free agent |
| 3/13 | Carl Nicks | G | declared free agent |
| 3/13 | Tracy Porter | CB | declared free agent |
| 3/13 | Jeff Charleston | DE | declared free agent |
| 3/13 | Courtney Roby | WR | declared free agent |
| 3/13 | Aubrayo Franklin | DT | declared free agent |
| 3/13 | Jo-Lonn Dunbar | LB | declared free agent |
| 3/13 | Shaun Rogers | DT | declared free agent |
| 3/13 | Leigh Torrence | CB | declared free agent |
| 3/13 | Ramon Humber | LB | declared free agent |
| 3/13 | Jonathan Casillas | LB | Restricted Free Agent |
| 3/13 | Marques Colston | WR | re-signed, Five-year extension (through 2016) |
| 3/12 | Chase Daniel | QB | re-signed, One-year extension (through 2012) |
| 3/9 | Turk McBride | DE | re-signed, One-year extension (through 2012) |
| 3/7 | Brian De La Puente | G | re-signed/exclusive rights free agent |
| 3/3 | Drew Brees | QB | Designated franchise player, Exclusive-rights franchise tag |
| 1/19 | Swanson Miller | DT | signed |
| 1/18 | Fenuki Tupou | T | signed |
| 1/18 | Phil Trautwein | T | signed |
| 1/18 | Chris Taylor | RB | signed |
| 1/18 | Kamaal McIlwain | CB | signed |
| 1/18 | Mitch King | DT | signed |
| 1/18 | Andy Tanner | WR | signed |
| 1/14 | Andy Tanner | WR | practice squad deletion |
| 1/14 | Sean Canfield | QB | practice squad addition |
| 1/9 | Andy Tanner | WR | practice squad addition |
| 1/9 | Sean Canfield | QB | practice squad deletion |
| 1/6 | Sean Canfield | QB | practice squad addition |
| 1/6 | Andy Tanner | WR | practice squad deletion |
| 1/3 | Will Herring | LB | Placed on IR, sprained right MCL |
| 1/3 | Mark Ingram | RB | Placed on IR, sprained left toe |
| 1/3 | Eric Olsen | G | signed |
| 1/3 | Nate Bussey | LB | Activated from the Practice Squad |
| 1/3 | Darry Beckwith | LB | practice squad addition |
| 1/2 | Andy Tanner | WR | practice squad addition |
| 1/2 | Sean Canfield | QB | practice squad deletion |
| 12/31 | Sean Canfield | QB | practice squad addition |
| 12/31 | Andy Tanner | WR | practice squad deletion |
| 12/28 | Tory Humphrey | TE | signed |
| 12/28 | William Robinson | T | cut |
| 12/27 | Andy Tanner | WR | practice squad addition |
| 12/27 | Sean Canfield | QB | practice squad deletion |
| 12/27 | Chris Taylor | RB | practice squad addition |
| 12/26 | Sean Canfield | QB | practice squad addition |
| 12/26 | Andy Tanner | WR | practice squad deletion |
| 12/20 | Sean Canfield | QB | practice squad deletion |
| 12/20 | Andy Tanner | WR | practice squad addition |
| 12/17 | Andy Tanner | WR | practice squad deletion |
| 12/17 | Sean Canfield | QB | practice squad addition |
| 12/10 | Sean Canfield | QB | practice squad addition |
| 12/10 | Andy Tanner | WR | practice squad deletion |
| 12/6 | Sean Canfield | QB | practice squad deletion |
| 12/6 | Andy Tanner | WR | practice squad addition |
| 12/3 | Sean Canfield | QB | practice squad addition |
| 12/3 | Andy Tanner | WR | practice squad deletion |
| 11/30 | Sean Canfield | QB | practice squad deletion |
| 11/29 | Andy Tanner | WR | practice squad addition |
| 11/28 | Andy Tanner | WR | practice squad deletion |
| 11/28 | Sean Canfield | QB | practice squad addition |
| 11/23 | Michael Higgins | TE | Activated from the Practice Squad |
| 11/23 | David Thomas | TE | Placed on IR, concussion |
| 11/23 | Daniel Hardy | TE | practice squad addition |
| 11/22 | Phil Trautwein | T | practice squad addition |
| More Transactions |
