| Last updated: Sat, May 26, 2012, 02:02 EDT |
| Date | Player | Pos. | Transaction |
| 5/24 | Dante Hughes | CB | signed |
| 5/24 | Brian Witherspoon | CB | cut |
| 5/14 | Will Hill | S | signed |
| 5/14 | Jake Muasau | LB | signed |
| 5/14 | Brandon Collins | WR | signed |
| 5/14 | Chad Jones | S | cut |
| 5/11 | Joe Martinek | RB | signed |
| 5/11 | David Douglas | WR | signed |
| 5/11 | Julian Talley | WR | signed |
| 5/11 | Rueben Randle | WR | signed/draft choice, Four-year contract (through 2015) |
| 5/11 | Jayron Hosley | CB | signed/draft choice, Four-year contract (through 2015) |
| 5/11 | Brandon Mosley | T | signed/draft choice, Four-year contract (through 2015) |
| 5/11 | David Wilson | RB | signed/draft choice, Four-year contract (fifth-year option) |
| 5/11 | Matt McCants | T | signed/draft choice, Four-year contract (through 2015) |
| 5/11 | JoJo Nicolas | S | signed |
| 5/11 | Adrien Robinson | TE | signed/draft choice, Four-year contract (through 2015) |
| 5/11 | Markus Kuhn | DT | signed/draft choice, Four-year contract (through 2015) |
| 5/11 | Stephen Goodin | G | signed |
| 5/11 | Adewale Ojomo | DE | signed |
| 5/11 | Matt Broha | DE | signed |
| 5/11 | Janzen Jackson | S | signed |
| 4/27 | Mathias Kiwanuka | LB | re-signed, Three-year extension (through 2015) |
| 4/26 | Shaun Rogers | DT | signed/unrestricted free agent |
| 4/21 | Zak DeOssie | LB | re-signed, Three-year extension (through 2015) |
| 4/17 | Chase Blackburn | LB | re-signed/unrestricted free agent, One-year contract (through 2012) |
| 4/16 | Antwaun Molden | CB | signed/unrestricted free agent |
| 4/15 | Bear Pascoe | TE | re-signed/exclusive rights free agent |
| 4/11 | Keith Rivers | LB | traded, for 5th-round pick in 2012 |
| 4/11 | Sean Locklear | T | signed/unrestricted free agent |
| 4/3 | Stevie Brown | S | signed/unrestricted free agent |
| 3/30 | Andre Brown | RB | suspended, 4 games (NFL Policy on PED's) |
| 3/22 | David Carr | QB | re-signed/unrestricted free agent, One-year contract (through 2012 |
| 3/16 | Steve Weatherford | P | re-signed, Five-year contract (through 2016) |
| 3/15 | David Carr | QB | re-signed/unrestricted free agent |
| 3/15 | Chris Horton | S | signed, One-year contract (through 2012) |
| 3/14 | Martellus Bennett | TE | signed/unrestricted free agent, One-year contract (through 2012) |
| 3/13 | Rocky Bernard | DT | declared free agent |
| 3/13 | Chase Blackburn | LB | declared free agent |
| 3/13 | Will Blackmon | CB | declared free agent |
| 3/13 | David Carr | QB | declared free agent |
| 3/13 | Michael Clayton | WR | declared free agent |
| 3/13 | Jonathan Goff | LB | declared free agent |
| 3/13 | Deon Grant | S | declared free agent |
| 3/13 | Jimmy Kennedy | DT | declared free agent |
| 3/13 | Joel Reinders | T | signed |
| 3/13 | Mario Manningham | WR | declared free agent |
| 3/13 | Derrick Martin | S | declared free agent |
| 3/13 | Kareem McKenzie | T | declared free agent |
| 3/13 | Aaron Ross | CB | declared free agent |
| 3/13 | Devin Thomas | WR | declared free agent |
| 3/13 | Dave Tollefson | DE | declared free agent |
| 3/13 | Tony Ugoh | T | declared free agent |
| 3/13 | Justin Tryon | CB | re-signed |
| 3/13 | Michael Coe | CB | re-signed |
| 3/13 | Terrell Thomas | CB | re-signed, Four-year extension (through 2015) |
| 3/13 | Larry Donnell | TE | signed |
| 3/13 | Stacy Andrews | T | declared free agent |
| 3/9 | Brandon Jacobs | RB | cut |
| 3/8 | Bruce Johnson | CB | re-signed/exclusive rights free agent |
| 3/8 | Jake Ballard | TE | re-signed/exclusive rights free agent |
| 3/5 | Steve Weatherford | P | Designated franchise player |
| 1/31 | Ryan Perrilloux | QB | practice squad addition |
| 1/31 | Selvish Capers | T | practice squad deletion |
| 1/23 | Selvish Capers | T | practice squad deletion |
| 1/23 | Ryan Perrilloux | QB | practice squad addition |
| 1/17 | Ryan Perrilloux | QB | practice squad deletion |
| 1/17 | Selvish Capers | T | practice squad addition |
| 1/10 | Ryan Perrilloux | QB | practice squad deletion |
| 1/10 | Selvish Capers | T | practice squad addition |
| 1/7 | Selvish Capers | T | practice squad deletion |
| 1/7 | Ryan Perrilloux | QB | practice squad addition |
| 12/21 | Selvish Capers | T | practice squad addition |
| 12/21 | Ryan Perrilloux | QB | practice squad deletion |
| 12/17 | Ryan Perrilloux | QB | practice squad addition |
| 12/17 | Selvish Capers | T | practice squad deletion |
| 12/7 | Stacy Andrews | T | Placed on IR, illness |
| 12/7 | Tony Ugoh | T | signed |
| 12/7 | Selvish Capers | T | practice squad addition |
| 12/7 | Ryan Perrilloux | QB | practice squad deletion |
| 12/6 | Selvish Capers | T | practice squad deletion |
| 12/6 | Ryan Perrilloux | QB | practice squad addition |
| 11/30 | Ryan Perrilloux | QB | practice squad deletion |
| 11/30 | Isaiah Stanback | WR | practice squad addition |
| 11/30 | Will Beatty | T | Placed on IR, eye |
| 11/30 | Chase Blackburn | LB | signed |
| More Transactions |
