| Last updated: Sat, May 26, 2012, 02:03 EDT |
| Date | Player | Pos. | Transaction |
| 5/24 | Justin Helwege | WR | signed |
| 5/23 | Cooper Helfet | TE | cut |
| 5/21 | Allen Barbre | T | suspended, 4 games (NFL policy on PED's) |
| 5/21 | Kellen Winslow | TE | traded, for 7th round pick in 2013 |
| 5/15 | Robert Turbin | RB | signed/draft choice, Four-year contract (through 2015) |
| 5/15 | Alex Barron | T | signed |
| 5/15 | London Durham | CB | cut |
| 5/15 | Adrian Moten | LB | cut |
| 5/15 | Andrew Mitchell | T | signed |
| 5/15 | Donny Lisowski | CB | signed |
| 5/15 | Cooper Helfet | TE | signed |
| 5/15 | Brent Osborne | C | cut |
| 5/15 | Jon Opperud | T | cut |
| 5/11 | Raymond Webber | WR | cut |
| 5/10 | Jaye Howard | DT | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Jeremy Lane | CB | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Winston Guy | S | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | J.R. Sweezy | G | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Greg Scruggs | DE | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Bruce Irvin | DE | signed/draft choice, Four-year contract (fifth-year option) |
| 5/7 | Korey Toomer | LB | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Russell Wilson | QB | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Bobby Wagner | LB | signed/draft choice, Four-year contract (through 2015) |
| 5/4 | John Graves | DE | cut |
| 5/4 | Jesse Hoffman | CB | cut |
| 5/4 | Raymond Webber | WR | acquired from waivers |
| 5/4 | Tressor Baptiste | LB | cut |
| 5/1 | Steven Hauschka | K | re-signed/restricted free agent, One-year contract (through 2012) |
| 4/29 | Lavasier Tuinei | WR | signed |
| 4/29 | Monte Taylor | DE | signed |
| 4/29 | Deshawn Shead | S | signed |
| 4/29 | Jon Opperud | T | signed |
| 4/29 | Phil Bates | WR | signed |
| 4/29 | Jermaine Kearse | WR | signed |
| 4/29 | Rishaw Johnson | G | signed |
| 4/29 | Carson Wiggs | K | signed |
| 4/29 | Sean McGrath | TE | signed |
| 4/29 | London Durham | CB | signed |
| 4/12 | Leroy Hill | LB | signed/unrestricted free agent, one-year contract |
| 4/12 | Matt McCoy | LB | signed/unrestricted free agent, one-year contract |
| 4/9 | Marcus Trufant | CB | signed, One-year contract (through 2012) |
| 4/6 | Roy Lewis | CB | re-signed/unrestricted free agent, One-year contract (through 2012) |
| 4/6 | Barrett Ruud | LB | signed/unrestricted free agent, One-year contract (through 2012) |
| 4/6 | Deuce Lutui | G | signed/unrestricted free agent, One-year contract (through 2012) |
| 3/23 | Kregg Lumpkin | RB | signed/unrestricted free agent |
| 3/21 | Frank Omiyale | T | signed/unrestricted free agent |
| 3/19 | Jarriel King | T | cut |
| 3/18 | Matt Flynn | QB | signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/17 | Jason Jones | DE | signed/unrestricted free agent, One-year contract (through 2012) |
| 3/16 | Michael Robinson | RB | re-signed/unrestricted free agent, Two-year contract (through 2013) |
| 3/15 | Paul McQuistan | G | re-signed/unrestricted free agent |
| 3/14 | Robert Gallery | G | cut |
| 3/13 | Red Bryant | DE | re-signed/unrestricted free agent, Five-year contract (through 2016) |
| 3/13 | Roy Lewis | CB | declared free agent |
| 3/13 | Mike Gibson | G | declared free agent |
| 3/13 | Kennard Cox | CB | declared free agent |
| 3/13 | Jimmy Wilkerson | DE | declared free agent |
| 3/13 | Charlie Whitehurst | QB | declared free agent |
| 3/13 | David Vobora | LB | declared free agent |
| 3/13 | Michael Robinson | RB | declared free agent |
| 3/13 | Paul McQuistan | G | declared free agent |
| 3/13 | Matt McCoy | LB | declared free agent |
| 3/13 | Leroy Hill | LB | declared free agent |
| 3/13 | David Hawthorne | LB | declared free agent |
| 3/13 | Anthony Hargrove | DE | declared free agent |
| 3/13 | Justin Forsett | RB | declared free agent |
| 3/13 | John Carlson | TE | declared free agent |
| 3/13 | Red Bryant | DE | declared free agent |
| 3/13 | Raheem Brock | DE | declared free agent |
| 3/13 | Atari Bigby | S | declared free agent |
| 3/13 | Steven Hauschka | K | Restricted Free Agent |
| 3/13 | Heath Farwell | LB | re-signed |
| 3/7 | Marcus Trufant | CB | cut |
| 3/4 | Marshawn Lynch | RB | re-signed, Four-year extension (through 2015) |
| 1/11 | Vai Taua | RB | signed |
| 1/5 | Charly Martin | WR | signed |
| 1/5 | Tyrell Sutton | RB | signed |
| 1/5 | Adrian Taylor | DT | signed |
| 1/3 | Jesse Hoffman | CB | signed |
| 1/3 | John Nalbone | TE | signed |
| 1/3 | John Graves | DE | signed |
| 1/3 | Coye Francies | CB | signed |
| 1/3 | Brent Osborne | C | signed |
| 1/3 | Pierre Allen | DE | signed |
| 1/3 | Allen Bradford | RB | signed |
| 12/20 | Phillip Adams | CB | signed |
| 12/19 | Mike Williams | WR | Placed on IR, broken leg |
| 12/14 | Ricardo Lockette | WR | Activated from the Practice Squad |
| 12/14 | Coye Francies | CB | practice squad addition |
| 12/13 | John Graves | DE | practice squad addition |
| 12/13 | Keith Darbut | LB | practice squad deletion |
| 12/13 | Ron Parker | CB | Placed on IR, Achilles |
| 12/6 | Jay Finley | RB | practice squad addition |
| 12/6 | Keith Darbut | LB | practice squad addition |
| 12/6 | Mike Gibson | G | signed |
| 12/6 | Russell Okung | T | Placed on IR, torn right pectoral muscle |
| 12/3 | Vai Taua | RB | practice squad deletion |
| 11/30 | Michael Morgan | LB | Activated from the Practice Squad |
| 11/30 | Sidney Rice | WR | Placed on IR, concussion |
| More Transactions |
