| Last updated: Sat, May 26, 2012, 02:03 EDT |
| Date | Player | Pos. | Transaction |
| 5/23 | Andy Lee | P | re-signed, Six-year extension (through 2018) |
| 5/14 | Ben Hannula | S | signed, Three-year contract (through 2014) |
| 5/14 | John Matthews | WR | cut |
| 5/14 | Eric Bakhtiari | LB | signed, Two-year contract (through 2013) |
| 5/14 | Kevin Murphy | T | cut |
| 5/11 | Cam Johnson | LB | signed/draft choice, Four-year contract (through 2015) |
| 5/10 | Trent Robinson | S | signed/draft choice, Four-year contract (through 2015) |
| 5/10 | Darius Fleming | LB | signed/draft choice, Four-year contract (through 2015) |
| 5/10 | Joe Looney | G | signed/draft choice, Four-year contract (through 2015) |
| 5/10 | LaMichael James | RB | signed/draft choice, Four-year contract (through 2015) |
| 5/10 | Jason Slowey | G | signed/draft choice, Four-year contract (through 2015) |
| 5/7 | Tony Jerod-Eddie | DT | signed |
| 5/4 | Jason Slowey | G | signed/draft choice, Four-year contract (through 2015) |
| 5/4 | Michael Thomas | S | signed |
| 5/4 | Brian Tyms | WR | signed |
| 5/4 | Giorgio Tavecchio | K | signed |
| 5/4 | Deante' Purvis | CB | signed |
| 5/4 | Nathan Palmer | WR | signed |
| 5/4 | Chris Owusu | WR | signed |
| 5/4 | Al Netter | G | signed |
| 5/4 | Kevin Murphy | T | signed |
| 5/4 | Anthony Mosley | CB | signed |
| 5/4 | Matthew Masifilo | DT | signed |
| 5/4 | Joe Holland | LB | signed |
| 5/4 | Jewel Hampton | RB | signed |
| 5/4 | David Gonzalez | G | signed |
| 5/4 | Cameron Bell | RB | signed |
| 5/4 | Kourtnei Brown | LB | signed |
| 5/4 | Patrick Butrym | DT | signed |
| 5/4 | Garrett Celek | TE | signed |
| 4/17 | Brett Swain | WR | re-signed/unrestricted free agent, One-year contract (through 2012) |
| 4/17 | Larry Grant | LB | re-signed/restricted free agent, One-year contract (through 2012) |
| 4/6 | Brett Swain | WR | re-signed/unrestricted free agent |
| 4/6 | Brandon Jacobs | RB | signed, One-year contract (through 2012) |
| 3/30 | Dontavia Bogan | WR | cut |
| 3/28 | Brandon Jacobs | RB | signed, One-year contract (through 2012) |
| 3/22 | Ted Ginn Jr. | WR | re-signed/unrestricted free agent, One-year contract (through 2012) |
| 3/22 | Josh Johnson | QB | signed/unrestricted free agent, Two-year contract (through 2013) |
| 3/22 | Mario Manningham | WR | signed/unrestricted free agent, Two-year contract (through 2013) |
| 3/21 | Alex Smith | QB | re-signed/unrestricted free agent, Three-year contract (through 2014) |
| 3/16 | Carlos Rogers | CB | re-signed/unrestricted free agent, Four-year contract (through 2015) |
| 3/16 | Rock Cartwright | RB | signed/unrestricted free agent, One-year contract (through 2012) |
| 3/15 | Shawntae Spencer | CB | cut |
| 3/13 | Perrish Cox | CB | signed, Two-year contract (through 2013) |
| 3/13 | Tavares Gooden | LB | re-signed, One-year extension (through 2012) |
| 3/13 | Larry Grant | LB | Restricted Free Agent |
| 3/13 | Blake Costanzo | LB | declared free agent |
| 3/13 | Ted Ginn Jr. | WR | declared free agent |
| 3/13 | Josh Morgan | WR | declared free agent |
| 3/13 | Moran Norris | RB | declared free agent |
| 3/13 | Justin Peelle | TE | declared free agent |
| 3/13 | Chilo Rachal | G | declared free agent |
| 3/13 | Carlos Rogers | CB | declared free agent |
| 3/13 | Alex Smith | QB | declared free agent |
| 3/13 | Reggie Smith | S | declared free agent |
| 3/13 | Adam Snyder | G | declared free agent |
| 3/13 | Madieu Williams | S | declared free agent |
| 3/13 | Brett Swain | WR | declared free agent |
| 3/12 | Randy Moss | WR | signed, One-year contract (through 2012) |
| 3/12 | Tramaine Brock | CB | re-signed/exclusive rights free agent |
| 3/8 | Will Tukuafu | DT | re-signed, Two-year extension (through 2013) |
| 3/6 | C.J. Spillman | S | re-signed, Three-year extension (through 2014) |
| 1/31 | Garrett Chisolm | G | signed |
| 1/31 | Kenny Wiggins | T | signed |
| 1/30 | John Matthews | WR | signed |
| 1/24 | Konrad Reuland | TE | signed |
| 1/24 | Michael Wilhoite | LB | signed |
| 1/24 | Cory Nelms | CB | signed |
| 1/24 | Mark LeGree | S | signed |
| 1/24 | Derek Hall | T | signed |
| 1/24 | Chase Beeler | C | signed |
| 1/24 | Kyle Nelson | TE | signed |
| 1/5 | Ricky Elmore | LB | practice squad addition |
| 1/5 | Bruce Davis | LB | practice squad deletion |
| 1/3 | Bruce Davis | LB | practice squad addition |
| 12/31 | Joe Hastings | WR | Activated from the Practice Squad |
| 12/27 | Braylon Edwards | WR | cut |
| 12/14 | Ian Johnson | RB | practice squad deletion |
| 12/14 | Michael Wilhoite | LB | practice squad addition |
| 12/8 | Alex Boone | T | signed, Four-year extension (through 2015) |
| 11/29 | Mark LeGree | S | practice squad deletion |
| 11/29 | John Matthews | WR | practice squad addition |
| More Transactions |
