Chris Ivory
Jaguars' Chris Ivory: Pleased with conditioning, ready to rumble
Chris Ivory, RB, JAC
9/30/2016
News: Ivory (ankle/knee) is pleased with his conditioning as the Jaguars prepare to face the Colts in London, the Florida Times-Union reports.

Despite missing the first two weeks with a still-undisclosed medical issue, Ivory seems to be at close to full strength ahead of Sunday's game. He was limited at Wednesday's practice due to minor knee and ankle injuries, but after logging full sessions both Thursday and Friday, his availability isn't in any question. With Ivory's health no longer the primary concern, attention shifts to his team's complete inability to open holes in the running game. Ivory gained just 14 yards on 12 carries in last week's loss to Baltimore, and T.J. Yeldon is averaging a meager 2.5 yards on his 34 totes this season. On a more optimistic note, Yeldon only took six carries last week, and the Colts aren't exactly a defensive powerhouse.

Analysis: 

C.J. Prosise
Seahawks' C.J. Prosise: Listed as questionable again
C.J. Prosise, RB, SEA
9/30/2016
News: Prosise (wrist/hand) is listed as questionable for Sunday's game against the Jets, Curtis Crabtree of Sports Radio KJR reports.

Per usual, head coach Pete Carroll provided conflicting statements, first saying that Prosise has a good shot to return for Week 4, but then clarifying that the rookie will still need a cast for another three weeks. Given that his role will largely revolve around his receiving skills, Prosise is unlikely to have a significant impact on offense until he sheds the cast. It's unclear if he actually has a shot to play in Sunday's game.

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Charcandrick West
Chiefs' Charcandrick West: Out this week
Charcandrick West, RB, KC
9/30/2016
News: West (ankle sprain) won't play Sunday night against the Steelers, BJ Kissel of Chiefs.com reports.

Though West is out this week, the Chiefs' backfield is poised to be bolstered by the anticipated return to action of Jamaal Charles. Assuming Charles and Spencer Ware -- who has been leading the team's rushing attack out of the gate this season -- can hold up, West's role once he regains his health figures to be limited.

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Jamaal Charles
Chiefs' Jamaal Charles: Reportedly poised to play this week
Jamaal Charles, RB, KC
9/30/2016
News: Though Charles (knee) will be listed as questionable for Sunday night's game against the Steelers, per BJ Kissel of the Chiefs' official site, ESPN's Adam Schefter reports that the running back is nonetheless expected to make his season debut this weekend.

After approaching the Chiefs' first three games listed as doubtful, it appears as though Charles is poised to see his first game action since suffering a torn ACL last October. Assuming he ends up in uniform Sunday night, we'd still expect to see a solid dose of fellow RB Spencer Ware, though with Charcandrick West ruled out this week, snaps will be up for grabs, which Charles and Knile Davis (to a lesser degree) are candidates to absorb.

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Kenyan Drake
Dolphins' Kenyan Drake: Two touches in Week 4
Kenyan Drake, RB, MIA
9/30/2016
News: Drake was given only two carries for 15 yards in Thursday night's loss to the Bengals.

Drake played only seven snaps Thursday, which was the lowest mark among the Dolphins' four running backs, Joe Schad of the Palm Beach Post reports. Considering the rookie is averaging 4.9 yards per carry, and fared well in limited touches again Thursday, his lack of involvement is somewhat questionable, but Miami's four-man committee approach in Arian Foster's (groin) absence limits Drake's fantasy upside anyways.

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Devonta Freeman
Falcons' Devonta Freeman: Returns to practice as full participant
Devonta Freeman, RB, ATL
9/30/2016
News: Freeman (illness) returned to practice as a full participant Friday and does not have an injury designation on the final report for Sunday's game against Carolina, ESPN's Vaughn McClure reports.

Tevin Coleman also logged a full practice and is slated to play in Sunday's game. Freeman and Coleman will continue to split work, forming a potent duo out of the backfield.

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Ka'Deem Carey
Bears' Ka'Deem Carey: Listed as doubtful
Ka'Deem Carey, RB, CHI
9/30/2016
News: Carey (hamstring) is listed as doubtful for Sunday's game against Detroit.

Carey didn't practice all week and can essentially be ruled out. With Jeremy Langford (ankle) also unavailable, rookie Jordan Howard is in line to lead the Chicago backfield.

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Jeremy Langford
Bears' Jeremy Langford: Technically listed as doubtful
Jeremy Langford, RB, CHI
9/30/2016
News: Langford (ankle) is listed as doubtful for Sunday's game against Detroit.

Langford is expected to miss four-to-six weeks, but the Bears for some reason prefer to list players as 'doubtful' rather than 'out'. With Ka'Deem Carey (hamstring) also listed as doubtful and not expected to play, Jordan Howard will likely serve as the lead back.

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DeAngelo Williams
Steelers' DeAngelo Williams: Still expected to get snaps
DeAngelo Williams, RB, PIT
9/30/2016
News: Williams should still see playing time despite teammate Le'Veon Bell returning from suspension.

Williams dominated the Steelers' backfield workload while Bell was suspended for the first three games of this season. Given that Bell is arguably the league's best tailback, he'll rightfully reclaim his leading role, but Pittsburgh's offense is still expected to use Williams going forward. While it remains to be seen just how many snaps and, more importantly, touches, Williams gets with Bell back in the fold, both players' well-rounded skill sets could allow the Steelers to get creative with their personnel in the weeks to come.

Analysis: 

Rashad Jennings
Giants' Rashad Jennings: Practices again Friday, but not as involved
Rashad Jennings, RB, NYG
9/30/2016
News: Jennings (thumb) took part in Friday's practice but was less involved than he was the day before, according to Newsday's Tom Rock.

Jennings has participated in the Giants' first two practice sessions of the week, but he was spotted with a larger wrap on his thumb than he had Thursday and took part in fewer drills than he did the day before, so his injured thumb does not appear to be trending in the right direction.

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