Tomlinson has not practiced since sustaining the injury in the season opener against the Bills. Jordan Leggett (knee) also did not practice, which leaves the reps at tight end to Will Tye and Austin Seferian-Jenkins, who is back from suspension.
Leggett has not practiced yet in the regular season, so it's hard to have any real expectations on when he could return. The rookie fifth-round pick missed a valuable opportunity now that Austin Seferian-Jenkins has been reinstated from his two-game suspension.
Heurerman went down with a shoulder injury during Sunday's loss to the Cowboys. He tallied one catch for 15 yards on his only target before being forced out of the game. A.J. Derby is next in line to back up Virgil Green at tight end if Heuerman is unable to take the field in Week 3.
Cook apparently came out of Sunday's 45-20 win over the Jets with a minor injury, but his ability to practice in some capacity suggests it's only a minor ailment. He's garnered a surprising generous target share through two weeks, accounting for 11 of Derek Carr's 60 pass attempts (18.3 percent). Next up in Week 3 is a Washington defense that's surrendered a league-high 208 receiving yards to tight ends.
Everett has thus far made the most of his role as the Rams' No. 2 tight end, parlaying four targets into four catches for a team-high 134 receiving yards. That production wouldn't be sustainable in his current role even if he were completely healthy, but he's at least making a case to eventually push Tyler Higbee for the No. 1 spot on the depth chart. Everett's inability to log a full practice during the week suggests he could be a game-day decision Thursday.
Bowles apparently isn't thrilled with how Seferian-Jenkins looked at Wednesday's practice after the tight end was away from the team for two weeks while serving a suspension. Regardless, it'll be a major surprise if Seferian-Jenkins isn't active Sunday, considering three of the team's other tight ends are recovering from injuries. Repeatedly mentioned as a standout throughout the offseason and training camp, Seferian-Jenkins could initially be eased into action with a limited workload, but he's still a clear favorite to emerge as the Jets' top tight end. Given the lack of the talent throughout the rest of the offense, he could eventually serve as Josh McCown's go-to option.
Held out of Monday's practice, Kittle managed limited participation Tuesday and Wednesday, likely setting him up to play Week 3. He played through the same injury the past two weeks, catching seven of eight targets for 40 yards while playing 92 percent of the offensive snaps.
McDonald logged just 18 snaps Week 1 and missed Week 2 with a back injury, but he could have a big role Sunday against the Bears if Jesse James' ankle injury turns out to be serious. Despite playing through the ailment in Sunday's win over the Vikings, James was held out of practice Wednesday.
James hurt his ankle during Sunday's 26-9 win over the Vikings, but that didn't stop him from playing 96 percent of the offensive snaps. Fellow tight end Vance McDonald, who missed the first two games with a back injury, wasn't listed on Wednesday's injury report. He'll likely take over as the starter if James isn't ready for Sunday's game in Chicago.
Griffin has passed through the concussion protocol and should be ready to return for Sunday's game in New England. With C.J. Fiedorowicz on injured reserve while recovering from a concussion of his own, Griffin is set to assume a role as the Texans' primary pass-catching tight end. Given the team's lack of depth at wide receiver, Griffin could be busy Week 3.